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Travel with the largest intercity bus service across the United States, Canada, and Mexico. The Greyhound Station in Florence operates daily, 9 a.m.-5 p.m. and 10 p.m.-11 p.m. Hours of operation are subject to change. Please call to verify hours before making travel arrangements.

611 S Irby Street
Florence, SC 29501
(843) 662-8407