Where to Shop

Florence, South Carolina is more than a convenient stop along I-95—it’s a thriving hub of locally owned shops filled with character, creativity, and Southern charm. From stylish boutiques to antique treasures and artisan markets, shopping local in Florence offers a one-of-a-kind experience you simply won’t find in big-box stores. Whether you’re searching for the perfect outfit, a meaningful gift, or a piece of home décor, Florence’s small businesses deliver both quality and personality.

 

Shop Downtown

Downtown Florence is at the heart of the local shopping scene. Over the past decade, this area has seen a vibrant revitalization, becoming a walkable destination filled with experiences. Jack’s Books is an independent bookstore with something for every reader. Pop into Barringer’s to purchase local gifts and get a real feel for the Florence area. Downtown Florence has also earned national recognition as a Great American Main Street.

Shoppers can explore unique boutiques like Agathoula’s for stylish clothing, accessories, and gifts for women of all ages. For those looking for fashion-forward finds with a personal touch, Summerlin’s Boutique provides a curated selection of clothing, accessories, and gifts designed to fit a variety of styles and sizes.

Shopping Places to Explore in Florence, SC

Static place cards remain readable before the live widget becomes interactive.

  • Clothing Store, Shopping, Second Hand | 1551 2nd Loop Rd, Florence, SC 29505, USA

    Palmetto Goodwill

    Welcome to Palmetto Goodwill, where every purchase makes a difference! More than just a retail store, we are a part of the community focused on giving back and providing opportu...

    Explore place
  • Shopping, National Brand Stores | 3311 E Palmetto St, Florence, SC 29501, USA

    Dollar General

    Welcome to Dollar General, your trusted partner in shopping for everyday needs! We pride ourselves on offering a wide selection of quality products at prices that won't break th...

    Explore place
  • Shopping, National Brand Stores, Johnsonville | 202 E Broadway St, Johnsonville, SC 29555, USA

    Dollar General

    Step into Dollar General and experience the joy of shopping where savings meet convenience! Our store is a true community staple, designed with your everyday needs in mind. From...

    Explore place
  • Clothing Store, Shopping, Second Hand | 260 N Beltline Dr, Florence, SC 29501, USA

    Palmetto Goodwill

    Welcome to Palmetto Goodwill, where every visit supports a greater cause! We invite you to explore our diverse selection of gently used items – from clothing to household goods,...

    Explore place
  • Shopping, National Brand Stores, Lake City Shopping | 238 Kelley St #11, Lake City, SC 29560, USA

    Roses Discount Store

    Welcome to Roses Discount Store, your ultimate shopping destination for incredible deals! Step into a world of unbeatable prices on a wide range of products, from fashion to hom...

    Explore place
  • Clothing Store, Shopping | 2701 David H McLeod Blvd #1410a, Florence, SC 29501, USA

    Lids

    Welcome to Lids, the go-to destination for headwear enthusiasts! From trendy caps to personalized gear featuring your favorite teams, we’ve got it all. Embrace your passion for...

    Explore place
  • Pharmacy, Shopping, Clothing Store, Health And Personal Care | 2791 David H McLeod Blvd, Florence, SC 29501, USA

    CVS Pharmacy

    Welcome to CVS Pharmacy, your trusted partner in health and wellness! Our store is dedicated to providing you with a full range of products and services, from prescription medic...

    Explore place
  • Clothing Store, Shopping, National Brand Stores | 2108 S Irby St, Florence, SC 29505, USA

    It's Fashion

    Welcome to It's Fashion, the trendy destination for style enthusiasts seeking the latest in fashion at amazing prices! Here, our shelves are stocked with fabulous clothing and a...

    Explore place
  • Shopping, Clothing Store, Gifts, Lake City Shopping | 124 E Main St, Lake City, SC 29560, USA

    Shade Tree Outfitters

    Welcome to Shade Tree Outfitters, where adventure meets comfort and style! Here, outdoor enthusiasts and nature lovers will find everything they need for their next expedition....

    Explore place
  • Shopping, National Brand Stores | 370 N Cashua Dr, Florence, SC 29501, USA

    Dollar General

    Welcome to Dollar General, your neighborhood one-stop shop where value meets variety! Whether you need everyday essentials, household supplies, or seasonal items, our doors are...

    Explore place
  • Shopping, National Brand Stores | 2604 S Irby St, Florence, SC 29505, USA

    Dollar General

    Welcome back to Dollar General, your friendly neighborhood store that offers unbeatable savings on a wide range of products! From groceries to home essentials, we are committed...

    Explore place
  • Shopping, National Brand Stores | 120 State Rd S-21-356, Florence, SC 29501, USA

    Dollar General

    Welcome to Dollar General, where convenience meets affordability! Featuring an extensive range of products, from household essentials to snacks and personal care items, this sto...

    Explore place
  • Shopping, National Brand Stores | 1418 E McIver Rd, Florence, SC 29501, USA

    Dollar General

    Welcome to Dollar General! This charming store is your friendly neighborhood stop for a diverse array of affordable merchandise. From grocery essentials to household supplies, D...

    Explore place
  • Clothing Store, Shopping | 2701 David H McLeod Blvd Space 1430, Florence, SC 29501, USA

    SNIPES

    Step into SNIPES, your go-to destination for the latest in trendy apparel and sneakers! Located in a lively part of Florence, SNIPES welcomes you with a vibrant atmosphere and a...

    Explore place
  • Clothing Store, Shopping, Formal Wear, Locally Owned | 1935 Hoffmeyer Rd, Florence, SC 29501, USA

    CYNTHIA-Apparel & Shoes

    CYNTHIA-Apparel & Shoes is your stylish pitstop in Florence that curates the latest trends in fashion! This welcoming boutique invites you to explore a diverse selection of appa...

    Explore place
  • Shopping, National Brand Stores | 2223 E Howe Springs Rd, Florence, SC 29505, USA

    Dollar General

    Welcome to Dollar General, your one-stop shop for convenience and savings! Here, you’ll discover an inviting store packed with everything you need, from household essentials to...

    Explore place
  • Shopping | 1526 S Irby St, Florence, SC 29505, USA

    H & Y Beauty Supply

    H & Y Beauty Supply Shopping located at 1526 S Irby St, Florence, SC 29505, USA

    Explore place
  • Clothing Store, Shopping, Second Hand | 2835 David H McLeod Blvd, Florence, SC 29501, USA

    Plato's Closet

    Plato's Closet Clothing Store, Shopping, Second Hand located at 2835 David H McLeod Blvd, Florence, SC 29501, USA

    Explore place
  • Shopping, Lake City Shopping, Shoe Store, National Brand Stores | 898 US-52 C, Lake City, SC 29560, USA

    Shoe Show Mega Store

    Shoe Show Mega Store Shopping, Lake City Shopping, Shoe Store, National Brand Stores located at 898 US-52 C, Lake City, SC 29560, USA

    Explore place
  • Pharmacy, Shopping, Health And Personal Care | 733 S Irby St, Florence, SC 29501, USA

    CVS Pharmacy

    At CVS Pharmacy, we prioritize your health and wellness with our open arms! Step into a place that feels more like a community hub than just a pharmacy—where friendly pharmacist...

    Explore place
  • Pharmacy, Shopping, Health And Personal Care | 2501 2nd Loop Rd, Florence, SC 29501, USA

    CVS Pharmacy

    Welcome to CVS Pharmacy, where your health and happiness are our top priorities! Here, we’re dedicated to providing a welcoming environment for all your pharmacy needs. From fil...

    Explore place
  • Shopping, National Brand Stores | 233 W Lucas St, Florence, SC 29501, USA

    Family Dollar

    Welcome to Family Dollar, your friendly neighborhood store packed with plenty of exciting finds! Here, you can explore a diverse selection of products at unbeatable prices, maki...

    Explore place
  • Shopping, National Brand Stores | 2838 W Palmetto St, Florence, SC 29501, USA

    Family Dollar

    Welcome to Family Dollar, your go-to destination for incredible savings and a friendly shopping experience! As you step inside, you'll be greeted with aisles filled with a varie...

    Explore place
  • Pharmacy, Shopping, Health And Personal Care | 2014 S Irby St, Florence, SC 29505, USA

    Walmart Pharmacy

    At Walmart Pharmacy, we are thrilled to provide you with a one-stop-shop for all your health and wellness needs! Our dedicated team is here to offer you friendly service in a co...

    Explore place
  • Shopping, Downtown Shopping, Gifts | 130 N Dargan St, Florence, SC 29506, USA

    Edible Arrangements

    Welcome to Edible Arrangements, where delicious meets delightful! This innovative shop transforms the ordinary into the extraordinary by crafting beautiful bouquets made entirel...

    Explore place
  • Shopping, Gifts, Jewelry Store, National Brand Stores | 2701 David H McLeod Blvd, Florence, SC 29501, USA

    Claire's

    Step into Claire's, where fashion meets fun! This delightful boutique is a treasure chest of trendy accessories, youthful styles, and sparkling jewelry for everyone. Whether you...

    Explore place
  • Shopping, Antiques, Farmer's Market, Furniture | 2513 W Lucas St, Florence, SC 29501, USA

    Two Girls Treasure

    Welcome to Two Girls Treasure, a charming boutique filled with unique finds and handmade creations! This inviting shop is a haven for treasure hunters looking for one-of-a-kind...

    Explore place
  • Pharmacy, Shopping, Gifts, National Brand Stores, Health And Personal Care | 2498 2nd Loop Rd, Florence, SC 29501, USA

    Walgreens Pharmacy

    At Walgreens Pharmacy, we put your health and wellness first! Our friendly team is dedicated to providing you with exceptional service, whether you're filling a prescription or...

    Explore place
  • National Brand Stores, Health And Personal Care, Pharmacy | 800 Pamplico Hwy, Florence, SC 29505, USA

    CVS

    Welcome to CVS, your neighborhood pharmacy that’s always here for you! At CVS, we are more than just a pharmacy; we are a trusted resource for health and wellness. Our friendly...

    Explore place
  • Lake City Shopping, Shopping, Locally Owned, Rental Supply Companies, Hardware Store | 914 S Ron McNair Blvd, Lake City, SC 29560, USA

    K G Smith CO INC

    K G Smith CO INC Lake City Shopping, Shopping, Locally Owned, Rental Supply Companies, Hardware Store located at 914 S Ron McNair Blvd, Lake City, SC 29560, USA

    Explore place
  • Pharmacy, Shopping, Health And Personal Care | 3306 W Palmetto St, Florence, SC 29501, USA

    CVS Pharmacy

    Welcome to CVS Pharmacy, where caring for your health is our mission! As a cornerstone of the community, we pride ourselves on providing high-quality pharmaceutical services alo...

    Explore place
  • Clothing Store, Shopping | 2701 David H McLeod Blvd, Florence, SC 29501, USA

    Klassic

    Klassic Clothing Store, Shopping located at 2701 David H McLeod Blvd, Florence, SC 29501, USA

    Explore place
  • Store, Second Hand, Gifts, Johnsonville | 210 E Broadway St, Johnsonville, SC 29555, USA

    Disabilities Thrift Shop

    Welcome to the Disabilities Thrift Shop, a vibrant hub that not only offers a diverse range of second-hand treasures but also promotes an incredible cause! Here, you're invited...

    Explore place
  • Shopping, Health And Personal Care, Pharmacy | 1500 S Irby St, Florence, SC 29505, USA

    Walgreens

    Welcome to Walgreens, your neighborhood pharmacy that’s more than just a store. We are committed to delivering personalized customer service with a warm smile, ensuring that eve...

    Explore place
  • Play, Outdoors, Sports Facilities, Sporting Goods | 937 Old Ebenezer Rd, Florence, SC 29501, USA

    Ebenezer Tennis Shop

    Step into the vibrant world of Ebenezer Tennis Shop, where passion for the game brings players of all levels together. Our shop is more than just a retail space; it's a welcomin...

    Explore place
  • Clothing Store, Shopping | 3041 W Radio Dr, Florence, SC 29501, USA

    SEPHORA at Kohl's

    Welcome to SEPHORA at Kohl's, where beauty meets convenience! We invite you to explore a treasure trove of cosmetics, skincare, and fragrance from your favorite brands, all unde...

    Explore place
  • Shopping, Antiques, Second Hand, Locally Owned | 1434 Pamplico Hwy, Florence, SC 29505, USA

    Shed

    Welcome to Shed, a delightful destination that celebrates community and creativity! Here, you'll find a warm atmosphere filled with local flavors and unique treasures. Whether y...

    Explore place
  • Clothing Store, Shopping, National Brand Stores | 2701 David H McLeod Blvd, Florence, SC 29501, USA

    Rainbow Shops

    Discover Rainbow Shops, a vibrant and trendy retail destination that welcomes fashion lovers of all ages! Here, you'll find a diverse range of stylish apparel and accessories at...

    Explore place
  • Shopping, Gifts, Jewelry Store | 2701 David H McLeod Blvd Shop #1108, Florence, SC 29501, USA

    Lovisa

    Welcome to Lovisa, where every piece of jewelry tells a story! Step into our store and immerse yourself in a world of dazzling designs and distinctive accessories that are perfe...

    Explore place
  • Shopping, Antiques | 1224 S Irby St Ste a, Florence, SC 29505, USA

    Carolina Collectables

    Step into Carolina Collectables, a charming store brimming with unique finds and treasured keepsakes! Here, you'll discover an array of delightful antiques and collectibles that...

    Explore place
  • Clothing Store, Shopping, National Brand Stores | 1945 W Palmetto St, Florence, SC 29501, USA

    Rainbow Shops

    Step into Rainbow Shops, where fashion meets affordability! Located conveniently for shopping enthusiasts, this colorful retail haven invites you to explore a diverse range of t...

    Explore place
  • Shopping, Health And Personal Care, Pharmacy | 3306 W Palmetto St, Florence, SC 29501, USA

    CVS

    Welcome to CVS, where caring for your health is our priority! Step inside our friendly pharmacy, and you’ll find a community-focused atmosphere ready to cater to your needs. Whe...

    Explore place
  • Shopping, Boutiques, Clothing Store, Johnsonville | 2853 Dawn Rd, Johnsonville, SC 29555, USA

    K & C Clothing

    Welcome to K & C Clothing, where style and community come together! As you enter this delightful shop, you’ll be greeted by a vibrant selection of fashionable clothing and acces...

    Explore place
  • Home Goods Store, Store | 531 3rd Loop Rd, Florence, SC 29505, USA

    Little Man Art and design

    Welcome to Little Man Art and Design, a creative oasis where imagination knows no bounds! Step into our vibrant space filled with artistic expression and innovation, where every...

    Explore place
  • Florist, Store, Johnsonville | 401 N Main St Ste a, Hemingway, SC 29554, USA

    Nana’s Busy Hands Florals & Decor, LLC

    Welcome to Nana’s Busy Hands Florals & Decor, LLC! Step into a delightful world filled with the beauty of nature and creativity. We are passionate about designing breathtaking f...

    Explore place
  • Store, Johnsonville, Shopping, National Brand Stores | 210 Country Club Dr, Johnsonville, SC 29555, USA

    Dollar tree

    Welcome to Dollar Tree, where everything is just a dollar! Step into a world full of possibilities and great savings, with an array of products for your everyday needs, crafts,...

    Explore place
  • Store, Establishment, Shopping, Gifts, Locally Owned, Play | 1090 Yellowstone Dr, Florence, SC 29505, USA

    Wendys Trendies

    Welcome to Wendy's Trendies, where fashion meets friendly service! Our boutique is a vibrant haven for style enthusiasts, offering trendy clothing and accessories that cater to...

    Explore place
  • Clothing Store, Shopping, Locally Owned | 814 W John Paul Jones Rd Rd2, Effingham, SC 29541, USA

    Summer Marie's Fashion & Things

    Step into Summer Marie's Fashion & Things, where style meets a sense of belonging! This enchanting boutique is not just a store; it's a haven for fashion enthusiasts and trendse...

    Explore place
  • Clothing Store, Shopping | 400 W Evans St, Florence, SC 29501, USA

    Foxy Ladies Boutique

    Welcome to Foxy Ladies Boutique, where fashion and friendliness go hand in hand! Immerse yourself in our welcoming environment filled with chic clothing, stylish accessories, an...

    Explore place
  • Gifts, Locally Owned, Shopping | 2151 W Evans St Ste E, Florence, SC 29501, USA

    Carolina Wren

    Welcome to Carolina Wren, your cozy escape into a world of charming gifts and home decor! Nestled in a friendly neighborhood, we take pride in curating a delightful selection of...

    Explore place

If JavaScript is disabled, this place listing remains readable in the raw HTML.

Gifts located at The Pharmacy Gifts

Shop for The Perfect Gift

If your taste leans toward home décor and gifts, Pieces Boutique & Gifts blends fashion with interior style. Meanwhile, The Pharmacy Gifts features thoughtfully curated home goods and unique gifts perfect for any occasion.

Pee Dee State Farmers Market

Shop with Artisans

Florence also shines when it comes to specialty and artisan shopping. The Pee Dee State Farmers Market and City Center Market bring together local farmers, makers, and small businesses offering fresh produce, handmade goods, and locally crafted products. These markets provide a direct connection between shoppers and the people who grow, create, and produce their goods, making every purchase more meaningful.

Places to Plunder in Florence, SC

Shop for Treasures

For treasure hunters, Florence is rich with antique shopping and eclectic finds. Spots like Palmetto Peddlers Antiques Mall and Carolina Trading Post offer everything from vintage décor to rare collectibles. The city’s shopping scene is known for its variety, with stores selling everything from retro furniture to handcrafted jewelry and art.

Shopping local in Florence isn’t just about what you buy—it’s about the experience. Each store tells a story, each owner brings passion to their craft, and every purchase supports the local economy. Whether you’re strolling through downtown, browsing a boutique, or discovering hidden gems in an antique shop, Florence invites you to slow down, explore, and shop with purpose.